Personal statement

Hi, I'm a PhD student at the university of Nice Sophia-Antipolis in the Institute of Chemistry.

I am working on chemical senses and I try to decipher the chemical basis underlying the sweet taste perception. I use molecular modeling tools to study the chemical structure of the already known sweeteners and molecular dynamic simulations to highlight key residues involved in their binding with the sweet taste receptor. I also analyse the molecular dynamic trajectories to get some clues in the GPCR class C activation mechanism.

I have a background in Biology and Bioinformatics. My three main hobbies are structural biology, Linux and Python programming language. During my PhD thesis, I manage practical works for first year BSc students (as teaching assistant) in the course "Structure of the atoms".


Publications

The anatomy of mammalian sweet taste receptors

JB Chéron, J Golebiowski, S Antonczak, S Fiorucci

Proteins: Structure, Function, and Bioinformatics

doi: 10.1002/prot.25228

2016


Sweetness prediction of natural compounds

JB Chéron, I Casciuc, J Golebiowski, S Antonczak, S Fiorucci

Food Chemistry

doi: 10.1016/j.foodchem.2016.10.145

2016


Job Experiences

PhD Student at University of Nice Sophia Antipolis

ICN, UMR 7272 - chemosim group

Topic: Molecular modeling study of the activation of transmembrane receptors involved in chemical senses.

Supervisors: Dr Sébastien Fiorucci and Pr Serge Antonczak

2014 - present


Structural biology internship at University of Bergen

CBU, Reuter Group

Topic: Docking of low molecular weight compounds in the active site of human Proteinase 3.

Supervisor: Pr Nathalie Reuter

2014
(6 months)


Structural biology internship at University of Paris Diderot

MTi, UMR 973

Topic: Comparison of the inhibitor-binding sites of type II topoisomerase.

Supervisors: Dr Leslie Regad and Pr Anne-Claude Camproux

2013
(4 months)


Electrophysiology internship at University of de Nantes

Institut du thorax, UMR 1087

Topic: Study of KCNQ1 channels voltage dependence.

Supervisor: Dr Gildas Loussouarn

2012
(2 months)


Structural biology internship at University of de Nantes

UFIP

Topic: Study of the activation of G protein-coupled receptors.

Supervisor: Dr Yves-Henri Sanejouand

2011
(1 month)


Education & Certification

MSc in in Silico Drug Design

Paris VII / University of Paris Diderot - France

2012-2014


BSc in Biology and Biochemistry

University of Nantes - France

2009-2012


Technical skills

Linux

90% Complete (success)

Windows

65% Complete

Python

90% Complete (success)

R

80% Complete (success)

C

40% Complete (danger)

Amber

85% Complete (success)

Gromacs

40% Complete (danger)

Pymol

85% Complete (success)

VMD

75% Complete (success)

Awards and Fellowships

Young researcher award - December 2016

Université Côte d'Azur

Grant in food science - July 2016

The Gen Foundation

Best oral communication - April 2015

SFCi, Nice - France

Travel Grant - October 2015

COST Action GLISTEN


Communications

Poster - June 2016

ISOT, Yokohama - Japan

Oral communication - April 2016

JFIC, Avignon - France

Broad audience communication - March 2016

International Perfume Museum, Grasse - France

Oral communication - October 2015

SFCi, Nice - France

Poster - September 2015

CECAM, Juelich - Germany

Poster - May 2015

GGMM, Sète - France

Poster - October 2013

SFCi, Nancy - France